Robert Downey : Tony Stark/Iron Man

Gwyneth Paltrow : Pepper Potts

Don Cheadle : Lt. Col. James "Rhodey" Rhodes

Scarlett Johansson : Natalie Rushman/Natasha Romanoff

Sam Rockwell : Justin Hammer

Mickey Rourke : Ivan Vanko

Samuel L. Jackson : Nick Fury

Clark Gregg : Agent Phil Coulson

John Slattery : Howard Stark

Garry Shandling : Senator Stern

Paul Bettany : Jarvis

Kate Mara : U.S. Marshal

Leslie Bibb : Christine Everhart

Jon Favreau : Happy Hogan

Christiane Amanpour : Herself

Philippe Bergeron : Detective Lemieux

James Bethea : Security Force #1

Michael Bruno : Security Force #2

Katie Clark : Expo Fan

Luminita Docan : Russian Newscaster

Francois Duhamel : French Photographer

Larry Ellison : Himself

DJ A.M. : Himself

Tim Guinee : Major Allen

Eric L Haney : General Meade